Ingredients & Warnings

Each bottle of SleepHealth contains 60 capsules, providing a 30-day supply following the suggested serving size and regimen.

Suggested Use:

Take 2 capsules approximately 30 minutes before your intended bedtime with or without food, or as directed by a trusted healthcare provider.

Ingredients:

300 mg  Olivamine®

[Olive Leaf Extract, Glycine, Taurine, MSM (methylsulfonylmethane), L-Proline, N-Acetyl-L-Cysteine, Vitamin B3 (niacinamide), Vitamin B6 (pyridoxine HCl)]

Plus:

Melatonin, Vitamin D, Magnesium, Solubilized Curcumin, Red Wine/Grapevine Extract Powder

Other Ingredients: Gelatin capsule (colored with FD&C Red#3, FD&C Blue#1, and titanium dioxide), microcrystalline cellulose, rice flour, magnesium stearate 

Warnings:

If you are pregnant, nursing, or taking other medications, consult your healthcare provider before using this product.  As is the case with all supplements, some individuals may not tolerate or may be allergic to the ingredients used.  Please read the ingredient panel carefully prior to ingestion.

Disclaimer:

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

 

About Olivamine®

The Precise Olivamine® Compound Blend is Scientifically Superior

The scientific community recognizes the tremendous health benefits of hydroxytyrosol, and the ever-increasing amounts of peer review literature on the subject makes this clear. This single ingredient makes the Olivamine® brand extraordinary. However, hydroxytyrosol in combination with the other Olivamine® compounds is scientifically superior.

Extensive and ongoing primary research, being conducted at the McCord Research Center located at Monash University in Melbourne, Australia, has demonstrated the superiority of the precise combination of compounds found in Olivamine®.

Researchers discovered that healing times in diabetic and nondiabetic models were substantially reduced following Olivamine® treatment. This is critical because improved repair helps ensure that a patient’s exposure to harmful infections and toxins is potentially reduced.

The Olivamine® supplement product line is not dependent upon secondary research. While others are doing excellent work, our research team is dedicated to discovering the benefits of the precise blend of compounds that allow our products to heal when nothing else works. There is a reason and it is scientific superiority.

Hydroxytyrosol Continues to Capture the Imagination of Scientists Around the World

As scientists develop more accurate experimental methods and improved technology to study cells at the molecular level using increasingly powerful microscopes, better gene analysis tools and faster ways to manipulate DNA and proteins, the ingredients in Olivamine® including hydroxytyrosol continue to reveal new exciting, cellular protection and repair activities. Moreover, vital clinical studies continue to demonstrate the remarkably positive effects Olivamine® has on cell health and repair.

Scientists can now observe hydroxytyrosol entering cells and interacting with important proteins that influence DNA expression, immune responses and cellular longevity. Not only can scientists study the effects of hydroxytyrosol on organelles like mitochondria, scientists are able to study the effects of hydroxytyrosol on so many cellular processes including endoplasmic reticulum stress. Changes in protein folding and DNA-protein interactions can now be examined.

The amazing ability of olive molecules, including hydroxytyrosol, to influence their molecular and cellular surroundings has captured the attention and imagination of scientist for many years, and is still proving to be extremely interesting and challenging. Teams of scientists are working hard to discover the many secrets still left to be revealed. The incredible ability of Olivamine® to improve the health of cells has stood the test of time and continues to promote exciting scientific and clinical breakthroughs.

Hydroxytyrosol Helps Regulate DNA Expression on the Epigenetic Level

The Olivamine® supplement product line was created over ten years ago, but the amazing science behind Olivamine® and the healing power of olives has held up against cutting-edge scientific scrutiny, and the knowledge gained from new discoveries related to Olivamine® has continued to expand at an ever-increasing rate.

One of the main components of olives is the molecule, hydroxytyrosol, a potent antioxidant that has been shown through scientific research to activate an array of beneficial genes and oxidative defense enzymes, as well as increase the lifespan of cells. Hydroxytyrosol helps protect the powerhouses of cells, known as mitochondria that are intimately involved in energy metabolism and aging. Hydroxytyrosol and a companion olive antioxidant decrease inflammation and increase endothelial cell viability and repair.

In the past few years, scientists have been able to determine thousands of genes that are positively affected by hydroxytyrosol. Not only does hydroxytyrosol influence the expression of so many important cellular proteins, hydroxytyrosol can help regulate DNA expression on the epigenetic level. Scientists are discovering more and more that epigenetics has major effects on cell development and growth, as well as repair.

Symptom Checker

Key Signs/Effects of Sleep Deprivation:

  • Excessive daytime sleepiness
  • Accidents from lack of attention
  • Moodiness
  • Hunger
  • Depression
  • Weight gain or weight loss

From the Pharmacist

Kyle Hilsabeck, PharmD., CWCP, is the Vice President of Pharmaceutical Affairs at McCord Holdings and licensed by the Iowa Board of Pharmacy with certifications in immunization, pharmaceutical compounding, and a Certified Wound Care Professional (CWCP). He completed degrees in biology and biochemistry at Wartburg College before earning his Doctorate of Pharmacy from the University of Iowa College of Pharmacy. Upon graduation, he completed a post-doctorate pharmacy practice residency through the University of Iowa. Dr. Hilsabeck worked in an advanced clinical practice retail pharmacy providing medication therapy management and precepting pharmacy students before joining the team at McCord Holdings. He has lectured for the University of Iowa College of Pharmacy on topics including dermatology therapeutics, vitamins, minerals, herbs, and nutritional supplements. Dr. Hilsabeck has a passion for improving patient care specifically with regards to the safety and quality of the products and health information people use.

Sound Sleep for a Sound Mind

Inadequate sleep is linked to long-term health risks including dementia and Alzheimer’s disease. Common pharmaceutical sleep aids tend to increase a person’s risk while more natural nutritional approaches including melatonin and magnesium appear to decrease cognitive risk while promoting better more restful sleep. [Continue Reading]

Resetting the Circadian Rhythm

Sleep disruptions have a negative impact on health but using safe and natural nutritional support including melatonin and magnesium can help reset the sleep clock and minimize restless nights and daytime drowsiness. Maintaining regular sleep patterns is essential for optimum health and feelings of wellness. [Continue Reading]

Prescription and OTC Sleep Aids Increase Risk of Dementia

Most over-the-counter & prescription sleep aids shouldn’t be used for over 2 weeks or in people 65+ due to side effects, falls, confusion, & even dementia. Safer alternatives including melatonin and magnesium can be used to support natural healthy sleep cycles without the same short and long term risks and side effects. [Continue Reading]

B Vitamins for Sleep and Energy

People typically associate B Vitamins with energy because there are high amounts of B Vitamins found in energy drinks and workout supplements. But B Vitamins produce a different type of energy than stimulants like caffeine. Some B Vitamins also play essential roles in healthy sleep, mood, and calming down nerves. [Continue Reading]

From the Scientist

Nancy B. Ray is the Science Officer for McCord Research. Dr. Ray currently writes about science and health issues and gives presentations related to the science of Olivamine® created by the founder of McCord Research, Dr. D. Elizabeth McCord. Dr. Ray received her Ph.D. in Biochemistry and Biophysics from Oregon State University. She was a postdoctoral fellow at NIH, Harvard University and Dana-Farber Cancer Institute, and the University of Iowa. As a fellow and research scientist she performed research in the areas of virology, immunology, and cancer. She also earned bachelor of science degrees in Chemistry and Microbiology at the University of Montana.

Getting Enough Sleep to Help Your Immunity

Many people experience insomnia that can contribute to inflammatory diseases including depression, diabetes and Alzheimer’s disease. Chronic sleep deprivation has negative effects on the immune system and may lead to increased infections. Melatonin, the hormone known to promote sleep can increase immunity and help those with chronic insomnia or jet lag. In addition, melatonin and magnesium found in SleepHealth may help decrease inflammation along with Olivamine®. Melatonin and Olivamine® also have antioxidant activities and may reduce oxidative stress that can result from persistent inflammation associated with chronic sleep deprivation. [Continue Reading]

Protecting Mitochondria for a Better Night’s Sleep

Mitochondria are known as the powerhouses of cells because they play a critical role in metabolism by producing energy. Most cells have a circadian clock that oscillates every 24 hours, and this rhythm influences sleep/wake cycles. Evidence indicates that metabolic and circadian processes are interconnected, and that greater metabolic activity and magnesium depletion can lead to oxidative stress that can damage cells and mitochondria, as well as result in disease. Lack of sleep due to magnesium depletion or other factors can also result in serious health problems including cardiovascular disease. Melatonin found in SleepHealth protects the circadian rhythm and mitochondria, and protects cells against oxidative stress along with many of the beneficial ingredients included in Olivamine®. [Continue Reading]

Peer Review Articles

Effects of the Olive-Derived Polyphenol Oleuropein on Human Health

Citation:

Barbaro B, Toietta G, Maggio R, et al. Effects of the olive-derived polyphenol oleuropein on human health. Int J Mol Sci. 2014;15(10):18508-18524. doi:10.3390/ijms151018508. [Read Article]

Oleuropein in Olive and its Pharmacological Effects

Citation:

Omar SH. Oleuropein in Olive and its Pharmacological Effects. Sci Pharm. 2010;78(2):133. doi:10.3797/SCIPHARM.0912-18. [Read Article]

MnSOD activity regulates hydroxytyrosol-induced extension of chronological lifespan

Citation:

Sarsour EH, Kumar MG, Kalen AL, Goswami M, Buettner GR, Goswami PC. MnSOD activity regulates hydroxytyrosol-induced extension of chronological lifespan. Age (Omaha). 2011;34:95-109. doi:10.1007/s11357-011-9223-7. [Read Article]

Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up

Citation:

Cao Y, Zhen S, Taylor AW, Appleton S, Atlantis E, Shi Z. Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up. Nutrients. 2018;10(10). doi:10.3390/nu10101354. [Read Article]

The Importance of Magnesium in Clinical Healthcare

Citation:

Schwalfenberg GK, Genuis SJ. The Importance of Magnesium in Clinical Healthcare. Scientifica (Cairo). 2017;2017:4179326. doi:10.1155/2017/4179326. [Read Article]

Meta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders

Citation:

Ferracioli-Oda E, Qawasmi A, Bloch MH. Meta-Analysis: Melatonin for the Treatment of Primary Sleep Disorders. PLoS One. 2013;8(5). doi:10.1371/JOURNAL.PONE.0063773. [Read Article]

Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks

Citation:

Hardeland R, Hardeland, Rüdiger. Aging, Melatonin, and the Pro- and Anti-Inflammatory Networks. Int J Mol Sci. 2019;20(5):1223. doi:10.3390/ijms20051223. [Read Article]

The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial

Citation:

Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, Rashidkhani B. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17(12):1161-1169. [Read Article]

Antiinflammatory Activity of Melatonin in Central Nervous System

Citation:

Esposito E, Cuzzocrea S. Antiinflammatory Activity of Melatonin in Central Nervous System. Curr Neuropharmacol. 2010;8(3):228-242. doi:10.2174/157015910792246155. [Read Article]

Oral Nonprescription Treatment for Insomnia : An Evaluation of Products With Limited Evidence

Citation:

Meoli AL, Rosen C, Kristo D, et al. Oral Nonprescription Treatment for Insomnia : An Evaluation of Products With Limited Evidence. J Clin Sleep Med. 2005;1(2):173-187. [Read Article]

The Economic Burden of Insomnia: Direct and Indirect Costs for Individuals with Insomnia Syndrome, Insomnia Symptoms, and Good Sleepers

Citation:

Daley M, Morin CM, LeBlanc M, Grégoire J-P, Savard J. The economic burden of insomnia: direct and indirect costs for individuals with insomnia syndrome, insomnia symptoms, and good sleepers. Sleep. 2009;32(1):55-64. [Read Article]

Effect of Light and Melatonin and other Melatonin Receptor Agonists on Human Circadian Physiology

Citation:

Emens JS, Burgess HJ. Effect of Light and Melatonin and Other Melatonin Receptor Agonists on Human Circadian Physiology. Sleep Med Clin. 2015;10(4):435-453. doi:10.1016/j.jsmc.2015.08.001. [Read Article]