Ingredients & Warnings

Each bottle of BrainHealth contains 60 capsules, providing a 30-day supply following the suggested serving size and regimen.

Suggested Use:

Take 2 capsules daily with or without food, or as directed by a trusted healthcare provider.

Ingredients:

300 mg  Olivamine®

[Olive Leaf Extract, Glycine, Taurine, MSM (methylsulfonylmethane), L-Proline, N-Acetyl-L-Cysteine, Vitamin B3 (niacinamide), Vitamin B6 (pyridoxine HCl)]

Plus:

Vitamin D, folate, Vitamin B12, Magnesium, Rhodiola Rosea, Solubilized Curcumin, Broccoli Extract, Green Tea Extract, Red Wine/Grapevine Extract Powder

Other Ingredients: Gelatin capsule (colored with FD&C Green#3, FD&C Yellow#6, and titanium dioxide), microcrystalline cellulose, rice flour, magnesium stearate

Warnings:

If you are pregnant, nursing, or taking other medications, consult your healthcare provider before using this product.  As is the case with all supplements, some individuals may not tolerate or may be allergic to the ingredients used.  Please read the ingredient panel carefully prior to ingestion.

 

Disclaimer:

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.

 

About Olivamine®

The Precise Olivamine® Compound Blend is Scientifically Superior

The scientific community recognizes the tremendous health benefits of hydroxytyrosol, and the ever-increasing amounts of peer review literature on the subject makes this clear. This single ingredient makes the Olivamine® brand extraordinary. However, hydroxytyrosol in combination with the other Olivamine® compounds is scientifically superior.

Extensive and ongoing primary research, being conducted at the McCord Research Center located at Monash University in Melbourne, Australia, has demonstrated the superiority of the precise combination of compounds found in Olivamine®.

Researchers discovered that healing times in diabetic and nondiabetic models were substantially reduced following Olivamine® treatment. This is critical because improved repair helps ensure that a patient’s exposure to harmful infections and toxins is potentially reduced.

The Olivamine® supplement product line is not dependent upon secondary research. While others are doing excellent work, our research team is dedicated to discovering the benefits of the precise blend of compounds that allow our products to heal when nothing else works. There is a reason and it is scientific superiority.

Hydroxytyrosol Continues to Capture the Imagination of Scientists Around the World

As scientists develop more accurate experimental methods and improved technology to study cells at the molecular level using increasingly powerful microscopes, better gene analysis tools and faster ways to manipulate DNA and proteins, the ingredients in Olivamine® including hydroxytyrosol continue to reveal new exciting, cellular protection and repair activities. Moreover, vital clinical studies continue to demonstrate the remarkably positive effects Olivamine® has on cell health and repair.

Scientists can now observe hydroxytyrosol entering cells and interacting with important proteins that influence DNA expression, immune responses and cellular longevity. Not only can scientists study the effects of hydroxytyrosol on organelles like mitochondria, scientists are able to study the effects of hydroxytyrosol on so many cellular processes including endoplasmic reticulum stress. Changes in protein folding and DNA-protein interactions can now be examined.

The amazing ability of olive molecules, including hydroxytyrosol, to influence their molecular and cellular surroundings has captured the attention and imagination of scientist for many years, and is still proving to be extremely interesting and challenging. Teams of scientists are working hard to discover the many secrets still left to be revealed. The incredible ability of Olivamine® to improve the health of cells has stood the test of time and continues to promote exciting scientific and clinical breakthroughs.

Hydroxytyrosol Helps Regulate DNA Expression on the Epigenetic Level

The Olivamine® supplement product line was created over ten years ago, but the amazing science behind Olivamine® and the healing power of olives has held up against cutting-edge scientific scrutiny, and the knowledge gained from new discoveries related to Olivamine® has continued to expand at an ever-increasing rate.

One of the main components of olives is the molecule, hydroxytyrosol, a potent antioxidant that has been shown through scientific research to activate an array of beneficial genes and oxidative defense enzymes, as well as increase the lifespan of cells. Hydroxytyrosol helps protect the powerhouses of cells, known as mitochondria that are intimately involved in energy metabolism and aging. Hydroxytyrosol and a companion olive antioxidant decrease inflammation and increase endothelial cell viability and repair.

In the past few years, scientists have been able to determine thousands of genes that are positively affected by hydroxytyrosol. Not only does hydroxytyrosol influence the expression of so many important cellular proteins, hydroxytyrosol can help regulate DNA expression on the epigenetic level. Scientists are discovering more and more that epigenetics has major effects on cell development and growth, as well as repair.

Symptom Checker

Brain Health may be beneficial for people experiencing:

  • Feelings of “brain fog”
  • Trouble concentrating
  • Trouble remembering things
  • Concerns about effects of aging on brain health

From the Pharmacist

Kyle Hilsabeck, PharmD., CWCP, is the Vice President of Pharmaceutical Affairs at McCord Holdings and licensed by the Iowa Board of Pharmacy with certifications in immunization, pharmaceutical compounding, and a Certified Wound Care Professional (CWCP). He completed degrees in biology and biochemistry at Wartburg College before earning his Doctorate of Pharmacy from the University of Iowa College of Pharmacy. Upon graduation, he completed a post-doctorate pharmacy practice residency through the University of Iowa. Dr. Hilsabeck worked in an advanced clinical practice retail pharmacy providing medication therapy management and precepting pharmacy students before joining the team at McCord Holdings. He has lectured for the University of Iowa College of Pharmacy on topics including dermatology therapeutics, vitamins, minerals, herbs, and nutritional supplements. Dr. Hilsabeck has a passion for improving patient care specifically with regards to the safety and quality of the products and health information people use.

Olivamine®: What is it? Science Behind the Supplements

Olivamine® is a patented antioxidant formula based on olive extracts with hydroxytyrosol and oleuropein plus supporting vitamins and amino acids. It was created to promote cellular health by activating mitochondrial antioxidants that are known to play a role in inflammation, disease, and longevity. [Continue Reading]

What’s So Special About Olives?

One of the features of the McCord Research products is they contain our special patented Olivamine remedy. As the name suggests, the formula is based on potent extracts from the olive containing hydroxytyrosol and oleuropein, two of the most potent antioxidants ever discovered, providing many of the health benefits. [Continue Reading]

Brain Health and Neurocognitive Disorders

Brain cells depend on a steady supply of nutrients and antioxidants to keep them healthy and functioning efficiently. Poor nutritional status can interfere with production of neurotransmitters and decrease neurological function, contributing to memory loss, confusion, mental fatigue, and more serious long term effects. [Continue Reading]

Security for Your Brain

The brain has a specialized security system called the blood brain barrier to protect it from internal and external harms. Aging, inflammation, & disease weaken the barrier allowing toxins & harmful chemicals into the brain, accelerating neurodegenerative processes especially related to oxidation & free radical damage. [Continue Reading]

From the Scientist

Nancy B. Ray is the Science Officer for McCord Research. Dr. Ray currently writes about science and health issues and gives presentations related to the science of Olivamine® created by the founder of McCord Research, Dr. D. Elizabeth McCord. Dr. Ray received her Ph.D. in Biochemistry and Biophysics from Oregon State University. She was a postdoctoral fellow at NIH, Harvard University and Dana-Farber Cancer Institute, and the University of Iowa. As a fellow and research scientist she performed research in the areas of virology, immunology, and cancer. She also earned bachelor of science degrees in Chemistry and Microbiology at the University of Montana.

Protecting the Brain with Taurine

Taurine is involved in many neurological activities and is also a powerful antioxidant that protects neurons from toxicities. Inflammation is associated with neurological diseases like Alzheimer’s and taurine has potent anti-inflammatory properties. Other Olivamine® ingredients protect the brain and can help provide the remedy for maintaining healthy levels of inflammation. [Continue Reading]

Folate Deficiency and Medications that Interfere with Folate Metabolism

Folate deficiency is linked with high homocysteine levels that have been associated with increased risk of cardiovascular disease.  Low levels of folate are also found in patients with rheumatoid arthritis. Certain drugs like methotrexate interfere with folate metabolism. Folate levels may also be low in people who take anti-epileptic drugs. Olivamine® MultiVitamin can help remedy folate deficiency. [Continue Reading]

How Olive Polyphenols Can Help Your Brain

The normal neuronal-vascular relationship is vital to healthy brain functioning. Cognitive decline and neurodegenerative diseases can result from endothelial dysfunction, oxidative stress and inflammation. The olive polyphenols hydroxytyrosol and oleuropein have potent activities that counteract oxidative stress and inflammation, and hydroxytyrosol has been shown to decrease endothelial dysfunction. Hydroxytyrosol along with other beneficial small molecules in Olivamine® found in Pinnaclife® BrainHealth are capable of crossing the blood brain barrier (BBB) to promote brain health. Damage to mitochondria that produce energy for brain cells is also associated with neurodegenerative diseases including Alzheimer’s and Parkinson’s disease. Oleuropein and hydroxytyrosol activate the major antioxidant defense enzyme, manganese superoxide (MnSOD) that can protect mitochondria from age-associated damage. [Continue Reading]

Peer Review Articles

Bioactivity of Olive Oil Phenols in Neuroprotection

Citation:

Angeloni C, Malaguti M, Barbalace MC, Hrelia S. Bioactivity of Olive Oil Phenols in Neuroprotection. Int J Mol Sci. 2017;18(11). doi:10.3390/ijms18112230. [Read Article]

Potential Role of Olive Oil Phenolic Compounds in the Prevention of Neurodegenerative Diseases

Citation:

Rodríguez-Morató J, Xicota L, Fitó M, Farré M, Dierssen M, de la Torre R. Potential Role of Olive Oil Phenolic Compounds in the Prevention of Neurodegenerative Diseases. Molecules. 2015;20(3):4655-4680. doi:10.3390/molecules20034655. [Read Article]

Cardioprotective and neuroprotective roles of oleuropein in olive

Citation:

Omar SH. Cardioprotective and neuroprotective roles of oleuropein in olive. Saudi Pharm J. 2010;18(3):111-121. doi:10.1016/J.JSPS.2010.05.005. [Read Article]

Glutathione deficiency leads to mitochondrial damage in brain

Citation:

Jain A, Mårtensson J, Stole E, Auld PA, Meister A. Glutathione deficiency leads to mitochondrial damage in brain. Proc Natl Acad Sci U S A. 1991;88(5):1913-1917. [Read Article]

N-acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic opportunities

Citation:

Shahripour RB, Harrigan MR, Alexandrov A V. N-acetylcysteine (NAC) in neurological disorders: mechanisms of action and therapeutic opportunities. Brain Behav. 2014;4(2):108-122. doi:10.1002/brb3.208. [Read Article]

Glutathione in Cerebral Microvascular Endothelial Biology and Pathobiology: Implications for Brain Homeostasis

Citation:

Li W, Busu C, Circu ML, Aw TY. Glutathione in cerebral microvascular endothelial biology and pathobiology: implications for brain homeostasis. Int J Cell Biol. 2012;2012:1-14. doi:10.1155/2012/434971. [Read Article]

Taurine improves the spatial learning and memory ability impaired by sub-chronic manganese exposure

Citation:

Lu C-L, Tang S, Meng Z-J, et al. Taurine improves the spatial learning and memory ability impaired by sub-chronic manganese exposure. J Biomed Sci. 2014;21(1):51. doi:10.1186/1423-0127-21-51. [Read Article]

Botanical phenolics and brain health

Citation:

Sun AY, Wang Q, Simonyi A, Sun GY. Botanical phenolics and brain health. Neuromolecular Med. 2008;10(4):259-274. doi:10.1007/s12017-008-8052-z. [Read Article]

Oxidants, antioxidants, and the degenerative diseases of aging

Citation:

Ames BN. Oxidants, Antioxidants, and the Degenerative Diseases of Aging. Proc Natl Acad Sci. 1993;90(17):7915-7922. doi:10.1073/pnas.90.17.7915. [Read Article]

Oral folic acid and vitamin B-12 supplementation to prevent cognitive decline in community-dwelling older adults with depressive symptoms—the Beyond Ageing Project: a randomized controlled trial

Citation:

Walker JG, Batterham PJ, Mackinnon AJ, et al. Oral folic acid and vitamin B-12 supplementation to prevent cognitive decline in community-dwelling older adults with depressive symptoms–the Beyond Ageing Project: a randomized controlled trial. Am J Clin Nutr. 2012;95(1):194-203. doi:10.3945/ajcn.110.007799. [Read Article]

Efficacy of curcumin for age-associated cognitive decline: a narrative review of preclinical and clinical studies

Citation:

Sarker MR, Franks SF. Efficacy of curcumin for age-associated cognitive decline: a narrative review of preclinical and clinical studies. GeroScience. 2018;40(2):73-95. doi:10.1007/s11357-018-0017-z. [Read Article]

Curcumin Protects Neuron against Cerebral Ischemia-Induced Inflammation through Improving PPAR-Gamma Function

Citation:

Liu Z-J, Liu W, Liu L, Xiao C, Wang Y, Jiao J-S. Curcumin Protects Neuron against Cerebral Ischemia-Induced Inflammation through Improving PPAR-Gamma Function. Evid Based Complement Alternat Med. 2013;2013:470975. doi:10.1155/2013/470975. [Read Article]

Inhibitory Effect on Cerebral Inflammatory Response following Traumatic Brain Injury in Rats: A Potential Neuroprotective Mechanism of N-Acetylcysteine

Citation:

Chen G, Shi J, Hu Z, Hang C. Inhibitory effect on cerebral inflammatory response following traumatic brain injury in rats: a potential neuroprotective mechanism of N-acetylcysteine. Mediators Inflamm. 2008;2008:1-8. doi:10.1155/2008/716458 [Read Article]