Short Read

  • Cells contain tiny "engines" called mitochondria that create the energy needed to function
  • Mitochondria require a wide array of vitamins, minerals, amino acids, and antioxidants to function properly
  • When mitochondria don't function properly it creates oxidative stress, inflammation, cell death, and diseases
  • Nutritional deficiencies contribute to poorly functioning mitochondria
  • Proper nourishment through diet and supplementation can help support mitochondria and keep them functioning properly

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The engine is arguably the most important part of the car. If it breaks down, the car loses the ability to perform its primary function. There are hundreds of small components within the engine that need to work in perfect synchronization and when just one piece of that machine is out of sync, the whole engine can shut down.  

Most of the cells in your body contain even more complicated “engines” called mitochondria (red blood cells do not).  Cells that require the most energy like those found in the brain, heart, kidneys, retinas and muscles may contain thousands of mitochondria in each cell.1 These tiny “engines” are responsible for converting the calories from dietary fats, proteins, and sugars into the energy that drives every process in your body.2 

Diagram of the Electron Transport ChainInstead of pistons, belts, spark plugs, valves, and fuel injectors that make a car engine run, the mitochondria rely on perfect synchronization of a complex system called the “electron-transport chain” (ETC).  The ETC is built with a combination of proteins, vitamins, minerals, co-enzymes, antioxidants, amino acids, and fatty acids.

When we are deficient in certain nutrients, the ETC does not work as well so mitochondria begin to malfunction and literally break down, causing the cell to die.2–6  It is no different than removing key components like spark plugs and pistons out of your engine and expecting it to run normally – it doesn’t work!

Engine Breakdown Causes Cell Death

Cell Dying by NecrosisCells typically die one of two ways: necrosis or apoptosis (app-uh-toe-sis).  Necrosis is when a cell dies due to things like mitochondrial dysfunction and trauma.7,8  Think of this like your car’s engine exploding and sending parts flying around causing damage to other parts of the car.  When cells die via necrosis, they similarly “explode” releasing metabolic waste products, free radicals, and inflammatory compounds causing inflammation and damage to surrounding cells and tissues. 

Cell dying by ApoptosisOn the other hand, when a cell dies of apoptosis it literally disassembles itself into tiny pieces called “blebs” that get absorbed and reused by surrounding cells.7,8  Think of this as an engine being carefully taken apart piece-by-piece so the parts can be reused to repair or build a new vehicle.  This is the way that cells are supposed to die, and they are actually genetically programmed to undergo this process when the time is appropriate.

Protecting Your Cellular Engines

When you provide your cells and the mitochondria with the materials they need, they are more likely to undergo apoptosis instead of necrosis.  This means providing them with an adequate supply of the vitamins, minerals, fatty acids, amino acids, and antioxidants that are needed for each and every component.  Better yet, some nutrients have even been shown to turn on genetic pathways that help make the system work even better.

Some of the major patented effects of Olivamine 10® Max relate to the effects that it has on specific genes for potent mitochondrial antioxidants.4,9–12  This combination of hydroxytyrosol from olives with amino acids, antioxidants, and other vital components of the electron transport chain including vitamins B3 and B6 has been shown to increase the lifespan of cells by as much as 20% while directing them towards apoptosis instead of necrosis when their lifespan is complete.  There can be even more benefit when Olivamine 10® Max is combined with other vital nutrients found in Pinnaclife nutritional supplements including:

  • Coenzyme Q10 (Co-Q10)6,13 in Pinnaclife® Multivitamin
  • Acetyl-l-carnitine14 in Pinnaclife® Multivitamin
  • Magnesium15 in Pinnaclife® D3+Magnesium, Mood Support, Brain Health, Sleep Support, and Joint Health
  • L-taurine16–18 in all products, but highest doses in Pinnaclife® Brain Health and Energy Support
  • Melatonin19 in Pinnaclife® Sleep Support

When you incorporate Pinnaclife Nutritional Supplements into your daily routine, it’s like you are providing your mitochondria with a supply of new parts plus a team of mechanics that are constantly working to keep your cellular engines running smoothly and efficiently.

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    10. Nguyen D, Hsu JW, Jahoor F, Sekhar R V. Effect of increasing glutathione with cysteine and glycine supplementation on mitochondrial fuel oxidation, insulin sensitivity, and body composition in older HIV-infected patients. J Clin Endocrinol Metab. 2014;99(1):169–77.
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    14. Ames BN, Liu J. Delaying the mitochondrial decay of aging with acetylcarnitine. Ann N Y Acad Sci. 2004;1033:108–16.
    15. Volpe SL. Magnesium in disease prevention and overall health. Adv Nutr. 2013;4(3):378S–83S.
    16. Chang L, Xu J, Yu F, Zhao J, Tang X, Tang C. Taurine protected myocardial mitochondria injury induced by hyperhomocysteinemia in rats. Amino Acids. 2004;27(1):37–48.
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    19. León J, Acuña-Castroviejo D, Escames G, Tan D-X, Reiter RJ. Melatonin mitigates mitochondrial malfunction. J Pineal Res. 2005;38(1):1–9.
  • Kyle Hilsabeck, PharmD., is the Vice President of Pharmaceutical Affairs at McCord Holdings and licensed by the Iowa Board of Pharmacy.  He completed bachelors degrees in biology and biochemistry at Wartburg College before earning his Doctorate of Pharmacy from the University of Iowa College of Pharmacy. Upon graduation, he completed a community pharmacy practice residency through the University of Iowa where he focused primarily on nutritional aspects of care including the use of vitamin, mineral, and herbal supplements.  He has taught courses for the University of Iowa College of Pharmacy on vitamins, minerals, herbs, and nutritional supplements and given many presentations on the subject as well.  He has a passion for improving patient care specifically with regards to the safety and quality of the nutritional supplements and health information people use.


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